Megurine is apart of the CV series where all of the surnames have "ne" at the end of the names meaning "sound". Meguri means either "circulate" or "around." Luka appeals to "nagare" where "lu" is spelled the same meaning "flow." But due to the Japananese language L is not pronounced and is replaced with R. Because of this it is common to see her called as Ruka. Ka means "song" or "scent."
So overall the name put together means mainly Circulate/around sound flowing song/scent.